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Ospreys dominate first half at Swansea.com Stadium, scoring four tries to Scarlets' one to lead 26-7 at the break.
Scarlets improve in second half but fail to take their chances, as Ospreys cruise to a 36-14 win to reach the quarter-finals
Ospreys will face Lyon in the last eight at the Swansea.com Stadium at 17:30 BST on Saturday, 12 April
Live Reporting
Matt Lloyd
Goodbye from Swanseapublished at 19:38 British Summer Time 6 April
19:38 BST 6 April
FT: Ospreys 36-14 Scarlets
Image source, Huw Evans Picture Agency
We expected a reaction from Ospreys after last week's league defeat at Llanelli and we got it.
Adam Beard got the scoring going after just two minutes before Jac Morgan, Rhys Davies, Dewi Lake, Jack Walsh and Dan Kasende completed an emphatic win for the hosts.
Blair Murray's early response hinted at more of a contest but Scarlets were made to pay for failing to capitalise on their chances.
Ospreys march into the quarter-finals as the last region flying the flag for Wales in Europe.
They now face French outfit Lyon here at the Swansea.com Stadium next Saturday, 12 April at 17:30 BST.
But you can follow all the build up on the BBC Sport website this week.
'We need a full 80 minutes' - Jonespublished at 19:36 British Summer Time 6 April
19:36 BST 6 April
FT: Ospreys 36-14 Scarlets
Image source, Huw Evans Picture Agency
Ospreys head coach Mark Jones told S4C: "I was very pleased with how we put the learnings from last week into action this week in that first half. We were very good.
"But I'm disappointed with the second half. There was a lack of execution and intent and if we want to progress in this tournament and reach a semi-final, then we need to play for the full 80 minutes.
"But the exciting thing is that we have won and there is still plenty to work on."
'It wasn't to be' for Scarlets - Peelpublished at 19:30 British Summer Time 6 April
19:30 BST 6 April
FT: Ospreys 36-14 Scarlets
Image source, Huw Evans Picture Agency
Scarlets head coach Dwayne Peel told S4C: "We're disappointed on our side, we thought we could put them under a bit of pressure but they started on fire scoring two early tries.
"The second-half I thought we needed to start early, but it wasn't to be.
"The positives for us is the way we kept battling.
"We've got the Dragons in two weeks, a lot of the players wouldn't have had a rest from the Six Nations so it'll be nice to have a week to resettle before playing again."
Postpublished at 19:26 British Summer Time 6 April
19:26 BST 6 April
FT: Ospreys 36-14 Scarlets
Ospreys captain Jac Morgan told S4C: "All credit to the boys they came out that first-half, we started well last week but our discipline let us down, we talked a lot about that this week and we were much better.
"We made a couple of changes from last week, but we're always ready as a squad and as a group of boys and we make sure whoever steps onto the pitch they put in a performance.
"We enjoyed playing in the quarter-finals last year and we can't wait to do it again at home."
Postpublished at 19:23 British Summer Time 6 April
19:23 BST 6 April
FT: Ospreys 36-14 Scarlets
Man of the match Dan Edwards told S4C: "We spoke in the week how important the first-half would be, just making sure we asked a lot from the Scarlets players.
"It's not often we get the sun down here, but the fans were great and we're hoping we can get more down next week."
Postpublished at 19:18 British Summer Time 6 April
19:18 BST 6 April
FT: Ospreys 36-14 Scarlets
Richie Rees Former Wales international on BBC Radio Wales
This is the best I've seen the Ospreys in a long long time, you can see the culture they're cultivating through Mark Jones and the rest of the coaching team.
WilliamsWilliams 66', substituted for Williams at 66 minutes
Number11,
GilesHopkins 71', substituted for Hopkins at 71 minutes
Number10,
D Edwards
Number9,
Morgan-WilliamsDavies 49', substituted for Davies at 49 minutes
Number1,
G ThomasPhillips 46', substituted for Phillips at 46 minutes
Number2,
LakeMorse 62', substituted for Morse at 62 minutes
Number3,
BothaMcGuigan 62', substituted for McGuigan at 62 minutes
Number4,
Davies
Number5,
BeardFender 53', substituted for Fender at 53 minutes
Number6,
J Morgan
Number7,
TipuricWarren 62', substituted for Warren at 62 minutes
Number8,
Morris
Substitutes
home team, Ospreys
Number16,
McGuigan
Number17,
Phillips
Number18,
Warren
Number19,
Fender
Number20,
Morse
Number21,
Davies
Number22,
Williams
Number23,
Hopkins
away team, Scarlets
Starting lineup
Number15,
B Murray
Number14,
Page
Number13,
RobertsNicholas 70', substituted for Nicholas at 70 minutes
Number12,
E James
Number11,
Mee
Number10,
Lloyd
Number9,
G DaviesJones 62', substituted for Jones at 62 minutes
Number1,
HepburnO'Connor 64', substituted for O'Connor at 64 minutes
Number2,
Eliasvan der Merwe 13', substituted for van der Merwe at 13 minutesElias 26', substituted for Elias at 26 minutesCraig 40', substituted for Craig at 40 minutes
Number3,
HM ThomasWainwright 40', substituted for Wainwright at 40 minutes
Number4,
Pricevan der Merwe 40', substituted for van der Merwe at 40 minutes
Number5,
Lousi
Number6,
FifitaTaylor 51', substituted for Taylor at 51 minutes
Number7,
MacleodDavis 62', substituted for Davis at 62 minutes
WilliamsWilliams 66', substituted for Williams at 66 minutes
Number11,
GilesHopkins 71', substituted for Hopkins at 71 minutes
Number10,
D Edwards
Number9,
Morgan-WilliamsDavies 49', substituted for Davies at 49 minutes
Number1,
G ThomasPhillips 46', substituted for Phillips at 46 minutes
Number2,
LakeMorse 62', substituted for Morse at 62 minutes
Number3,
BothaMcGuigan 62', substituted for McGuigan at 62 minutes
Number4,
Davies
Number5,
BeardFender 53', substituted for Fender at 53 minutes
Number6,
J Morgan
Number7,
TipuricWarren 62', substituted for Warren at 62 minutes
Number8,
Morris
Substitutes
Number16,
McGuigan
Number17,
Phillips
Number18,
Warren
Number19,
Fender
Number20,
Morse
Number21,
Davies
Number22,
Williams
Number23,
Hopkins
away team, Scarlets
Starting lineup
Number15,
B Murray
Number14,
Page
Number13,
RobertsNicholas 70', substituted for Nicholas at 70 minutes
Number12,
E James
Number11,
Mee
Number10,
Lloyd
Number9,
G DaviesJones 62', substituted for Jones at 62 minutes
Number1,
HepburnO'Connor 64', substituted for O'Connor at 64 minutes
Number2,
Eliasvan der Merwe 13', substituted for van der Merwe at 13 minutesElias 26', substituted for Elias at 26 minutesCraig 40', substituted for Craig at 40 minutes
Number3,
HM ThomasWainwright 40', substituted for Wainwright at 40 minutes
Number4,
Pricevan der Merwe 40', substituted for van der Merwe at 40 minutes
Number5,
Lousi
Number6,
FifitaTaylor 51', substituted for Taylor at 51 minutes
Number7,
MacleodDavis 62', substituted for Davis at 62 minutes