From the structure of DNA to the electron and neutron, some of the most significant scientific discoveries have been made in the Cavendish Laboratory.
Founded 150 years ago to house the physics department at the University of Cambridge, the lab has relocated twice to ensure its facilities kept pace with its science.
Now, it's new home is the Ray Dolby Centre, named after the former Cambridge student who brought us surround-sound.
A team of 1,000 scientists are now hoping to etch their own names in history inside the new base.
Janine Machin went to visit a lab like no other.
